 Wysłany: Pon 19:20, 28 Lut 2011 Temat postu: mbt italia 抗MHCⅡ类抗 |
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抗MHCⅡ类抗原单克隆抗体人血清蛋白氨甲喋呤结合... manostcogenicsarco—maeells．CancerResI986，46(占)；24076NoriakiE，eta1．1nvitrocYtotoxi—cityofahumanSC1~Unlalbumin—me一·dintedconiugateofmethotrexatewi恤-anti—MM46monocloHalantibody．CancerRes1987；47(4)_107B．(收稿1989—12—26修回1990—0I一04)．CharacteristicsofaHumanSerumAlbumin—MediatedConjugateofMethotrexatewithAnti—MHCClassIIMonoclonalAntibodyHaoLet，MangWenx~e。，ShenSuyun,moncler paris，HuShenhui．Sm,Bfnzhong。TanWeiquanandChenZhang(DepartmentofHematology，XijingHospital,UGG Boots Outlet，TheFourthMilitaryMedicalUniversity．Xiall710032)(DepartmentofToxicologyTheFourthMilitaryMedicalUniversity，Xil&n710032)(InstituteofHematology，ChineseAcademyofMedicalSciencesTianjing300020)AbsttactInthestudiesonantibody—drugconjugaLosaspotentiaipurgingagentsiNhonemarrowtransplantatlon．MTx，coupledwithHSAbymeansofcarbondiimide,ugg botas，WasconiugatedwithakindofmurinemonoclonalantibodytoMHCⅡantigenusingHSA0sanjntermediafor．州TX．HSAwasCOndjtionedtohaveabout】toolofthiolgrouppertoolofHSAbydithiothreltoltreatment．theresultingSH—HSA—MTXthenbeingreactedwithimmunoglobulinmodiliedwiththePDPgroup．Theconjugates~H148一HSA—MTx,Moncler pas cher，whichinhibited80ofgrowthra№oftargetcell—Rajiand40ofgrowthrateofnontargetcell—Molt4atadoseof&tg／mlofMTx，retainedbothantibodylbindinganddrugactivities．ThecytotoxicitywalockedbyunconjugatedHi43．WhentheconjugatesreachedthedosagecapableofmaximalkillingRajicells。therewas11otoxicitytomuItipotentiaIprogenito：s(CFU—GM，innormalhumanbonemarrow．Key~"aordsantibodies，monoclonaljmethotrexate；cytot0xicity；MHCclassIIanti—genantibody—drugcoajugate More articles related to topics： tiffany deutschland MICA基因与器官移植及前景_1915 ugg italia ICU危重患者中心静脉压的测定及护理分析_1 ugg boots ireland 赵淳从中医络病理论论治急性冠脉综 |
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