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Wysłany: Wto 8:50, 14 Gru 2010
Temat postu: ugg boots España 6 cases of acute interstitial pne
AIP no significant gender differences in incidence, average age 49 years [2], no specific clinical features. This paper reports the 6 patients were cough, progressive dyspnea aggravated, there are hot 4 / 6, skin rash 1 / 6,
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, sputum, blood, 2 / 6, such as performance. The average duration of symptoms 18d, most no more than 60d [3]. AIP pathology is characterized by diffuse alveolar damage,
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, is divided into exudative and proliferative phase, exudation of the pathological features of alveolar epithelial basement membrane as well as injury, inflammatory cells into the alveolar cavity in the damaged alveolar wall visible on the lung cell type Ⅱ epithelial cell regeneration,
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, and replacement of alveolar epithelial type I, see also spotty distribution of exfoliated epithelial cells and by fibrin transparent film composed of the alveolar cavity filling, and alveolar edema and alveolar hemorrhage separated. Increasingly visible in the alveolar fibroblast cell components,
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, leading to alveolar fibrosis. Period characterized by the proliferation of alveolar and alveolar septum showed significant fibrosis and thickening of alveolar septum, mainly of fibroblasts and myofibroblasts, accompanied by mild collagen deposition [3].
2 Discussion
1 clinical data
6 patients have received 2 ~ 7d-day broad-spectrum antibiotic therapy, treatment failure; 5 patients in the 2d to 4 weeks after admission using mechanical ventilation (2 patients non-invasive ventilation, endotracheal intubation in 3 cases); were successively (2 ~ 17d) use of corticosteroid therapy (methylprednisolone 160mg ~ 500mg), 5 ~ 7d later changed to conventional dose (0.5 ~ 1mg/kg); 2 cases of female patients after methylprednisolone pulse therapy after the original two 320mg consolidation under the shadow of significant absorption, 1 case reviewed after 3 months of basic dissipated chest CT showed lesions, 1 case 1 month later was absorbed chest CT showed lesions (see inside back cover Fig. 9); 1 patients with symptoms after hormone therapy early eased, but the reduction in the hormone during the rapid deterioration (see inside back cover Fig. 10); more than 3 patients intubated mechanical ventilation died shortly after treatment is still not correct respiratory failure.
AIP is idiopathic interstitial pneumonia in a unique clinical - images - an independent disease pathology. In recent years, due to its unique clinical and pathological, American Thoracic Society and European Respiratory Society is that the AIP is different from idiopathic pulmonary fibrosis an interstitial lung disease [1].
Select from April 2005 to December 2007 admitted to Sir Run Run Shaw Hospital, 6 cases of AIP patients,
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, of which 3 were male and 3 females, mean age (63.67 ± 1.73) years; course 6d ~ 1 month on average (46.47 ± 6.94) d; 6 patients showed an increase in short-term dry cough and progressive dyspnea. 1 case complicated course of disease in the mediastinum and subcutaneous emphysema, 1 case of subcutaneous emphysema. Physical examination showed 6 patients were significantly increased respiratory rate, lung sounds can be heard and Velcro. Laboratory tests: white blood cell count 4.81 × 109 / L ~ 15.50 × 109 / L, erythrocyte sedimentation rate 13mm/hr ~ 89mm/hr; 1 例 ANA1: 100 particle type; arterial blood gas analysis showed type I respiratory failure, and there were decreased PaO2 , oxygenation index <200 (76.84 ~ 197.61). 6 patients have varying degrees of image changes. By CT were classified into six: normal images (1 min), ground glass-like changes (2 points), consolidation (3 points), ground glass-like changes with traction bronchiectasis (4 points), consolidation with traction bronchiectasis (5), honeycombing (6 points), by measuring the lung area on each side of the lung for each of the three exceptions to obtain the total score range. 6 patients with CT score of 12 to 28 minutes.
6 cases of Acute Interstitial Pneumonia
<div style=\ Key words acute interstitial pneumonia
Acute interstitial pneumonia (acute interstitial pneumonitis, AIP) is a diffuse infiltration of the lung and the rapid development of respiratory failure characterized by pulmonary disease, idiopathic interstitial pneumonia is a subtype. In this study, 6 cases of AIP in patients with clinical features, treatment and prognosis after conducting a retrospective study. More articles related to topics:
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