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<table border="0" cellpadding="3" cellspacing="1" width="100%" class="forumline"> <tr> <th class="thCornerL" width="22%">Autor</th> <th class="thCornerR">Wiadomość</th> </tr> <tr> <td width="22%" align="left" valign="top" class="row1"><span class="name"><a name=""></a><b>52sale5126am</b></span></td> <td class="row1" valign="top"><table width="100%" border="0" cellspacing="0" cellpadding="0"> <tr> <td width="100%"><img src="http://picsrv.fora.pl/Elveron/images/icon_minipost.gif" width="12" height="9" alt="Post" title="Post" border="0" /><span class="postdetails">Wysłany: Pią 12:49, 11 Mar 2011<span class="gen"> </span> Temat postu: mbt shoes on sale Par-4 antisense oligonucleotide</span></td> </tr> <tr> <td colspan="2"><hr /></td> </tr> <tr> <td colspan="2"><span class="postbody">Par-4 antisense oligonucleotide antagonist of glutamate on PC12 cells, phosphorylation of protein kinase Akt1 down effect and significance of anti-apoptosis <br /> <br /> <br />Break down resistance to the oligonucleotide (Wai 1) 3. 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This confirms pBr4 glutamate may be involved in apoptosis of machine hood. using antisense oligonucleotide inhibits pm'-4 gene expression at the same time, PCI2 cells induced by glutamate Bute on the role of power is inhibited apoptosis. This shows that p ~ r-4 antisense oligonucleotide can be antagonistic character of nitrogen acid induced death of PC12 cells poke. We found that glutamate can induce phosphorylation of PCI2 cells (Thr308) of Akt down, while transfection of antisense oligonucleotide _4 selection can be significantly under the effect of inhibition of blame . If I PI3K/Akt antagonist. the par-4 antisense oligonucleotide on apoptosis induced by glutamate antagonism is a certain degree of reduction. 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